Sativa versus Indica: what is the difference and does it matter?

Sativas will give you energy, Indicas will leave you ‘in da couch.’ That’s how cannabis strains have been differentiated for decades, especially here in North America, but is that truth, or just a trope?

Turns out, it’s less fact than fiction. 

Thanks to genomic studies, we now know cannabis is in fact one plant that has been bred into separate uses, thanks largely to selection by humans over the last 12,000 years.

The study found cannabis varieties can be traced to four main groups, which originated in what is today China, India, Pakistan and Tibet, basically the Himalayan mountains. 

What we call Cannabis Sativa and Cannabis Indica, is actually just Cannabis. 

Back at the end of the Ice Age about 12,000 years ago, when humans began moving from being small groups of mainly hunter gatherers to the advent of farming, one of the first plants we domesticated was cannabis.

Because those mountain ranges are unforgiving, people on one side wouldn’t have interacted with, or even known about those on the other. So their uses of the plant differed greatly, resulting in the plant becoming what we call Cannabis Sativa and Cannabis Indica. 

The use in what today would be China and southeast Asia was mainly as a textile. The word ‘Sativa’ is Latin and means ‘cultivated’.

The earliest records we have come from the Shen Nong Ben Cao Jing, which is dated to around 2700BC and is linked to the mythical Chinese emperor

The earliest records we have around Cannabis Indica come from the Vedas, scripture from ancient India dated between 2000BC and 1400BC. The stories about cannabis are linked to the god Shiva, and it was known by its Sanskrit name, ganja, which is still widely used today.

The earliest written use of ‘Cannabis Sativa’ comes from William Turner’s Book of Herbs, published in the 1500s and it was officially classified in 1753 by botanist Carl Linnaeus. Then in 1785, fellow botanist Jean-Baptiste Lamarck proposed the wild cannabis found in India, which was largely consumed as a drug, was different enough that it should be ascribed as well. 

Since then, the debate has continued.

According to Dr. Matt Hill, a respected researcher at the University of Calgary, there is no empirical evidence to show a difference between the effects of consuming sativa versus indica. Instead, he says it comes largely down to expectations when consuming and I would tend to agree. 

When choosing a strain, one way of approaching is: if your nose likes the smell, your brain will enjoy the effect.

THC is THC, you couldn’t put it under a microscope and say whether it came from a ‘sativa’ or ‘indica’ plant. Instead, it is the entourage effect, several compounds working together, which makes consuming different strains feel different. Set and setting matter.

In fact, we didn’t even know what THC was until 1964, when it was discovered by Dr. Raphael Mechoulam. 

We also have to consider that nearly a century of illegality in North America means female plants were pollinated with whatever male plants were available, so hybridization was rampant. 

*Sidenote: along with sativa and indica, there is also a third type of cannabis, Ruderalis, which is found on the steppes of southern Russia and largely does not have cannabinoids.

The Discovery of THC

Dr. Raphael Mechoulam

Dr. Raphael Mechoulam

People have been getting stoned off Cannabis for thousands of years, but it’s only been the last half century that we’ve understood why.

It was in 1964 at the Weizmann Institute of Science in Rehovot, Israel that Dr. Raphael Mechoulam, along with colleagues Dr. Yehiel Gaoni and Dr. Haviv Edery, first isolated delta-9-tetrahydrocannabinol, which we know as THC.

This began our journey of understanding of the mechanisms behind how and why we get high when we consume decarboxylated Cannabis — which continues today — and led to the discovery of cannabinoid receptors in the human brain and the endocannabinoid system in the human body.

Mechoulam and his colleagues also isolated several more of the 113 cannabinoids that have been found so far, including CBD.

In a 2011 interview with High Times Magazine, Mechoulam said that Cannabis wasn’t well known in the U.S. at the time, mostly being used by jazz musicians. We know this wasn’t entirely accurate, though, as Cannabis was being used in most states and the underground industry was growing.

Because it was illegal in many countries by the 1960s, there was little research being done on the plant. As an organic chemist, Mechoulam was interested in biological activity and it was the lack of knowledge or ongoing research that drew him to Cannabis.

He had asked for a research grant from the American-based National Institute of Health (NIH), which turned him down. But they became interested after Mechoulam managed to isolate 10 grams of THC from hashish.

Despite Cannabis being illegal in Isreal, Mechoulam said they were able to do research as the government understood they weren’t selling it on the side. As we say so often, it was a different time back then.

Why the NIH suddenly got involved is also an interesting story, as told to High Times by Mechoulam:

“Yeah, well, they [NIH] didn’t have a single grant on cannabis at that time, but the National Institute of Mental Health did, I think. As I said earlier, the NIH wrote me that they don’t want to, they won’t give me money, because it’s not interesting or relevant. And then, all of a sudden, I get a phone call from the head of pharmacology at NIH, and they’re now interested. So I asked him: “What happened, all of a sudden, that you have great interest?” Well, it turned out that a senator had called NIH – his son smoked pot, and he wanted to know whether it would destroy his mind!

And just like that, the government got NIH to change direction. They don’t want to fight the senators because they need their support, and they looked around and [said] “Aha!” – they don’t support grants on marijuana, so they asked me if I was still working. We had just isolated THC, and that was it.”

Along with illegality, our lack of knowledge also came from the fact isolating THC was not an easy thing to do, as Mechoulam explained to High Times:

See, morphine and cocaine are so-called alkaloids, namely a natural product that contains a nitrogen [atom] on the molecule, and it can give us salt; it precipitates as a salt. And so you have salt: Cocaine is a salt, morphine is a salt – very easy to prepare. It turned out that THC does not have a nitrogen, and it is present in a mixture of compounds – we know that there are about 60 of them now. And they didn’t have the techniques to isolate them in the past. So a few people tried here and there, actually some very good people – one of them [Lord Alexander Todd] got the Nobel Prize for something else. But they never succeeded in isolating the pure substance, and so they never knew whether they had one compound or many compounds, and so on.

Our understanding of THC has grown since that initial breakthrough. We now know there are CB1 and CB2 receptors in our bodies and brains, and that THC binds to these, giving us euphoric effects.

We also now know that when we smoke Cannabis, it becomes decarboxylated and the delta-9-THC molecules are carried from our lungs to our brains via capillaries. But when we eat decarboxylated Cannabis, our livers break the delta-9-THC molecule down, creating the metabolite 11-OH-THC, which is believed to be one of the reasons why edibles last much longer and are stronger than flower.

Another positive that will come from legalization is the fact it makes research easier to undertake, which will expand our understanding further.

To hear Mechoulam tell the story himself, watch this brilliant documentary:

The History of Bongs

"Hits From The Bong" by Cypress HillListen to Cypress Hill: https://CypressHill.lnk.to/listenYDSubscribe to the official Cypress Hill YouTube channel: https:...

Pick it, pack it, fire it up, come along, and take a hit from the bong
Put the blunt down, just for a second, don’t get me wrong, it’s not a new method

There's a lot of truth in Cypress Hill's hit song, Hits From the Bong.

The water does smell like shit on the carpet if you spill it; it does go down smooth when you get a clean hit; and bongs are most definitely not a new method.

They’ve been a staple in dorm rooms and head shops since the 1970s, but the use of bongs dates back much further than that. Thousands of years, in fact.

A bong — also known as a bubbler or a water pipe — has a chamber, that’s usually partially filled with water, with a stem (where you put the Cannabis) and a tube or mouthpiece to draw smoke from.

Just about anything can be made into a bong, from an apple to a milk jug, and advances in manufacturing mean they’re becoming more and more ornate, with multiple chambers.

Drawing smoke through water is thought to cool it down and filter out some of the plant material and tar, but studies show it also filters out some of the cannabinoids.

Our understanding of the history of bongs has only really come into focus in the last decade. Until recently, it was believed bongs were first used in Africa starting in the 1100s by tribes in the southern and eastern parts of the continent, as those were the oldest examples found.

Bongs were then carried into Asia, and throughout the rest of the known world via the Silk Road starting around the 1400s, with the advent of smoking.

But our knowledge was expanded in 2013 with the discovery of a 2,400-year-old kurgan — a Scythian burial mound — in what is today southern Russia.

Inside were two ornate, solid gold bongs dating to around 400BC — about 1,500 years earlier than the earliest bongs discovered in Africa. Residue from inside the ancient Scythian relics tested positive for both Cannabis and opium, a combination that’s known as an A-Bomb today.

You can read more about the discovery and see photos in a National Geographic article here.

As recounted by the Greek historian Herodotus in his work The Histories around 430BC, the Scythian consumed Cannabis as a way of communing with the spirit world, and subsequent discoveries suggest Cannabis was consumed regularly by both men and women.

Life would have been tough as a marauding warrior around the fourth century BC, so it’s not surprising they used it to find pleasure and relaxation.

Ancient Scythian artisans obviously didn’t craft the first bongs out of solid gold. They likely evolved from handheld wooden and clay braziers — small carved or moulded containers that could be filled with cannabis, then hot stones or pebbles would be placed on top and the smoke and vapour inhaled.

Scythian culture has strong ties to the history of Cannabis. As is explained in a previous post, their word for it — Kanab — is widely considered the origin of the word Cannabis.

The Scythian were also responsible for spreading Cannabis use across what is today Europe, the Middle East and North Africa. They brought it to Greece (where we get the word Kannabis), and some ancient Arabic scholars said it was brought to the Levant countries around 1100 by mongol invaders.

It makes sense then that Cannabis and the use of bongs would have been carried into Egypt, and then spread further south to places like modern-day Ethiopia around that time.

The English word, ‘bong’ comes from the Thai word 'baung’ which dates to around the 14th century and means a tube, usually made from bamboo, that’s used to smoke Cannabis or tobacco. The Thai word might itself come from the Bong’om tribe in Africa.

The earliest written use of the English word ‘bong’ was in a 1944 Thai-English dictionary by George Bradley McFarland, so it’s plausible the word could have been brought to North America by soldiers returning from the Pacific theatre during the Second World War.

Bongs became popularized in North America in the 1960s and 70s with the growth of plastic, acrylic and glass manufacturing and by soldiers returning from Vietnam.

Canada's first Cannabis dealers

William DeBozy.

William DeBozy, an American who was arrested in January 1938 in Windsor, and later sentenced to three years jail.

by Dave Dormer

George Charbonneau likely had no idea RCMP Sgt. Ted Weeks was waiting for him when he boarded the LaSalle Ferry on Dec. 4, 1937 for the 15-minute return trip from Detroit to Windsor, Ont.

In the pockets of his overcoat on that chilly Saturday, the 21-year-old Canadian was carrying just over five ounces of ground cannabis hidden in two tobacco tins.

Reefer Madness was ramping up as cannabis had been made illegal in the U.S. two months earlier (14 years after it was made illegal in Canada) and enforcement was increasing on both sides of the border.

According to a 1938 League of Nations report on illicit transactions and seizures of drugs, RCMP suspected Charbonneau of trafficking cannabis and Weeks, along with Const. Robinson of the Windsor detachment, were waiting to search him when he arrived at the dock.

LaSalle Ferry Windsor-Detroit 2.jpg

The LaSalle Ferry ran between Detroit and Windsor from 1922 to 1938.

Newspaper reports from the time say police suspected “marijuana” — the pejorative term for cannabis — was driving a rise in youth crime in Windsor and they wanted to stamp it out.

The bust was a big deal at the time.

A story on Page 12 of the Globe and Mail on Dec. 6, 1937 declared it “the largest seizure ever made of the drug here.”

RCMP also mentioned it in their year-end report dated March 31, 1938.

Charbonneau opted for a speedy trial by judge alone in Essex County Court, and 32 days after being arrested, on Jan. 5, 1938, he was found guilty by Judge JJ Coughlin. He was sentenced to two-years-less-a-day, plus a further indeterminate term of not more than one year, and fined $200. That’s equal to about $3,600 in 2020 dollars and Charbonneau was to be jailed for another month if he didn’t pay the fine.

That makes Charbonneau one of Canada’s first convicted cannabis smugglers.

Who was George Charbonneau?

We don’t have a lot of information but public records are able to paint a small picture.

Charbonneau was raised in a blue-collar, Francophone family in Windsor, Ont.

He was born Sept. 30, 1916, in Windsor, Ont. the oldest of six children (three sons and three daughters) to parents Louis and Mellina Charbonneau.

Copy of the 1921 Canadian census, which lists the Charbonneau family.

The family spoke French as their first language, but also spoke English, and George was listed as Roman Catholic on both the 1921 census and his court record.

His father, Louis, was a house painter and owned the modest brick home the family lived in on Dufferin Avenue in Windsor. Louis also passed away in 1932, when George was about 16 so it makes sense he might have wanted to earn extra money for the family during the Great Depression, but that is speculation.

Court records say Charbonneau (his name is spelled Charboneau on some reports) had an elementary school education and was working as a labourer when he was arrested.

At that time, he was living close to where he grew up, in a house on Bridge Avenue, about six kilometres from the Detroit-Windsor ferry dock.

Charbonneau would have had a supplier on the U.S. side as Cannabis doesn’t grow outdoors in the winter and indoor growing wasn’t yet a thing. Some police reports say officers suspected cannabis was being grown in Mexico and the southern U.S., and brought up to the northeast.

A quarter pound (4 ounces) of cannabis goes for around $600 today and he had a little more than that on him (5 1/8 ounces) when he was busted.

According to public records, Charbonneau joined the armed forces after his sentence and served in Second World War, along with brother Earl. George served with the Essex and Kent Scottish Regiment and was injured while overseas with the Canadian forces in Normandy.

He later married Hilda Fretwell and the couple had three children and six grandchildren.

Charbonneau passed away at his home in Tilbury, Ont. on May 31, 1987.

New record bust

The seizure of five ounces of cannabis was the largest ever in Canada at the time, but that record didn’t last for long.

Just 10 days after Charbonneau was jailed — on Jan. 15, 1938 — RCMP arrested 31-year-old William DeBozy, who they suspected was a main supplier of Cannabis to the Windsor area.

DeBozy, an American from Plymouth, Mi., and his girlfriend, Cora Arnold, from Detroit, were being tailed by narcotics officers in Windsor on that Saturday.

The couple was stopped in DeBozy’s car, a Ford Tudor, which he’d driven over the border. A police report says he worked for the Ford Motor Company at the time.

According to the 1938 League of Nations report, neither had drugs on them when they were stopped and searched, but police found a package of 25 cannabis cigarettes hidden under the dashboard.

DeBozy admitted the joints were his so he was arrested and Arnold was released without charge. A police officer escorted her back to Detroit.

Interestingly, police later learned Arnold had been jailed briefly for cannabis possession in Michigan, meaning she might not have been such an innocent bystander.

DeBozy’s car was taken to a garage to be searched and after using a large metal hook found on the backseat to open a hidden compartment in the trunk, police discovered eight tobacco tins filled with about 21 ounces of cannabis — a new record bust.

Police suspected DeBozy was growing cannabis on his farm near Plymouth, Mi. and he was one of the main suppliers to the Windsor area.

His lawyer, Gerald McHugh, argued it was for personal use and DeBozy had found the cannabis growing wild in a vacant lot near his home.

He told court he’d picked up the habit of smoking “reefers” while serving in the U.S. army in Panama.

DeBozy initially pleaded not guilty, but at a hearing on Jan. 24, 1938, he changed his plea to guilty and was sentenced to three years in Kingston Penitentiary plus a $200 fine (and another six months if he didn’t pay it).

His car was also confiscated.

In his mug shot, DeBozy is wearing a white dress shirt, dark jacket and a hat, and has a resigned look on his face.

Newspaper archives say one of his sisters shouted “Oh no!” when the sentence was read out in court and she had to be escorted from the room, sobbing, causing a short delay.

Interestingly, DeBozy was asked by Crown prosecutor Keith Laird — who also prosecuted Charbonneau — during the proceedings: “Are you aware that marihuana causes murderous intent in some people?”

To which he replied, “No, it never affects me that way.”

DeBozy died in Michigan in 1962 at the age of 55.

Earliest arrests linked to jazz musicians

The first arrests for cannabis in Canada, according to newspaper reports, happened on June 13, 1933 in Montreal, involving three musicians from the U.S. and a Canadian.

The musicians were part of a 15-piece orchestra at Frolics Cabaret, which operated at 1417 Saint-Laurent Blvd. from 1929 to 1933. The club was quite opulent in its day, with the owners investing $50,000 to convert a fur warehouse, which would be nearly $1 million today.

It was known for having silk tapestries on the walls, a large dance floor and and high-end lighting, attracting socialites, celebrities and gangsters from as far away as New York.

A months-long investigation had been launched into the suspected sale of “marijuana cigarettes” in Montreal, which eventually led to the cabaret.

On that Tuesday night, officers were surveilling the musicians and “shortly after midnight,” two of them, Sam Burman (it’s also spelled Burnham), 28, from Toledo, Ohio, and Charlie Walker, 25, from Savannah, Georgia, were followed to a rooming house on Crescent Street, not far away, where they were staying.

The two were arrested and a search of the room turned up a tobacco tin containing 150 cannabis cigarettes, which was seized.

Another musician, Joseph Banks, 29, from New York, and the only Canadian, Arthur Gravel, 24, arrived a few minutes later, and they were also arrested.

According to the 1931 census, Gravel was Francophone and had grown up in Montreal. He was single and lived in a rented apartment with his mother and 33-year-old sister and was listed as working as a clerk.

Another interesting tidbit from the census is that Gravel reported earnings of $480 in the previous 12 months.

Their bails were set at $3,000 each, which was an enormous sum at the time, especially during the Depression years, equivalent to about $70,000 in 2026.

Because drugs were prosecuted as a summary offence, there was no preliminary inquiry, instead the cases went to trial by judge and 10 days later, three of the four were convicted.

Burman, who is described in newspapers as a “negro cabaret entertainer” was jailed for six months and handed a $200 fine by Judge Victor Cusson.

The fact that “negro” and “colored” was the first, and sometimes only, descriptor of the musicians in almost every newspaper story is evidence of the coded language of the day.

Racism was less prevalent in Canada than the U.S., especially in Montreal, which was a larger centre than Toronto at the time, but it was still part of life.

Banks and Gravel were given similar sentences of six months in jail and a fine, while Walker was acquitted.

Walker being acquitted is somewhat surprising. My theory is he didn’t have any cannabis on him when he was arrested, so he couldn’t be tied to the tins.

Records also show the affects cannabis prosecutions had on people. In the census record before his arrest, Gravel’s occupation is listed as clerk, but later records list him as a day labourer.

In an unrelated move, two days after the arrests, Frolics Cabaret was rebranded as a jazz club called Connie’s Inn, largely the result of Prohibition having been ended in the U.S., meaning the number of American visitors was waning.

Another newspaper story says “mariajuana” (sic) was mainly used in the south but cigarettes with the drug were being found the year before in New York, and they had begun showing up ‘on the fringes of Montreal nightlife.’”

Another interesting fact is that two month earlier, in April 1933, Harry Davis, who was an original investor in Frolics Cabaret, was arrested after police found 850 kilograms of heroin hidden in a shipment of Japanese silk. Officers had been investigating suspected drug trafficking for nearly three years and the seizure was made after a gang member turned informant.

Davis was convicted in October 1933 of drug smuggling and bribing customs officers and was sentenced to 14 years in prison, along with 10 lashes. That makes him the first person in Canada to be sentenced to lashes for a drug offence.

Many earlier court documents and police files have been destroyed by fire over the years, and many of the available records only list ‘drugs,’ so we don’t know definitely they meant cannabis.